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Checkpoint Responses in Cancer Therapy
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Publisher: Humana Press Number Of Pages: 314 Publication Date: 2008-05-01 ISBN-10 / ASIN: 1588299309 ISBN-13 / EAN: 9781588299307 Binding: Hardcover
Product Description: Extensive research has uncovered a set of molecular surveillance mechanisms – commonly called “checkpoints” – which tightly monitor cell-cycle processes. Today’s anticancer drug development has identified many of these cell-cycle checkpoint molecules as effective targets. Research now promises to uncover a new generation of anticancer drugs with improved therapeutic indices based on their ability to target emerging checkpoint components. Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs.
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Posted in books by UGLYBOYS
on May. 09, 2008 // 13:08
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