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Surface Contamination and Cleaning

This volume documents the proceedings of the International Symposium on Surface Contamination and Cleaning, held in Newark, New Jersey, May 23-25, 2001. Because of the importance of this topic in many technological areas, tremendous efforts have been devoted to devise novel and more efficient ways to monitor, analyse and characterize contamination on surfaces as well as ways to remove such contamination from a wide variety of surfaces. The technological areas where surface contamination has always been a bete noire and thus surface cleaning is of cardinal importance are too many and range from aerospace to microelectronics to biomedical. This volume contains a total of 24 papers, all rigorously peer reviewed and revised before inclusion, which deal with all kinds of contaminations on a host of surfaces. The topics covered include: mapping of surface contaminants; various techniques for cleaning surfaces; various techniques for monitoring level of cleanliness; acceptable cleanliness levels; ionic contamination; pharmaceutical cleaning validations; cleaning of glass surfaces; decontamination of sensitive equipment; no-chemistry process cleaning; waterjet cleaning; cleaning with solid carbon dioxide pellet blasting; cleanroom wipers; dust removal from solar panels and spacecraft on Mars; laser cleaning of silicon surfaces; particle removal; implications of surface contamination and cleaning; and future of industrial cleaning and related public policy-making. This volume offers a wealth of information and represents current commentary on the R&D activity taking place in the technologically highly important field of surface contamination and cleaning and should be of value and interest to anyone interested in the fundamental or applied aspects of this topic.

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Posted in books by kdsaggi on Nov. 13, 2008 // 10:36 | Comments (0)
Liquid Chromatography Column Theory

Offers comprehensive coverage of all the theoretical aspects of chromatography columns beginning with very simple concepts which describe their properties. Topics include peak capacity, column overload, thermal effects and many other chromatographic phenomena. Provides in-depth discussions of both the plate and rate theories as well as the design of the optimum column, analytical packed and open tubular columns. Includes practical examples of the use of these theories and equations derived from them.

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Posted in books by kdsaggi on Nov. 13, 2008 // 10:37 | Comments (0)
Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays

Safety aspects have become an outstanding issue in the process of drug discovery and development. Until 15 years ago, drug discovery and evaluation was a sequential process starting with the selection of the most active compound from a series of newly synthesized compounds by means of special pharmacological assays. Safety aspects were addressed by pharmacological testing of the selected compound in high doses in tests directed at indications other than the intended indication of the new compound. These tests were followed by pharmacokinetic studies, which were mainly aimed at confirming of a suitable half-life time and at oral activity. Safety aspects relied mostly on toxicity studies, which however gave Read more...
Posted in books by kdsaggi on Nov. 13, 2008 // 10:42 | Comments (0)
Statistical Design and Analysis of Stability Studies

The US Food and Drug Administration's Report to the Nation in 2004 and 2005 indicated that one of the top reasons for drug recall was that stability data did not support existing expiration dates. Pharmaceutical companies conduct stability studies to characterize the degradation of drug Read more...

Posted in books by kdsaggi on Nov. 13, 2008 // 10:43 | Comments (0)