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Nanoparticulate Drug Delivery Systems
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Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.
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Posted in books by kdsaggi on Nov. 08, 2008 // 06:47
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Nanotechnology for Cancer Therapy
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Encouraging communication between clinical investigators and nanoscientists, Nanotechnology for Cancer Therapy focuses specifically on effective and promising nanoscience and nanotechnology strategies for imaging and treating cancer. Among the various approaches considered, nanotechnology offers the best promise for the targeted delivery of drugs and genes to a tumor site and for alleviating side effects of chemotherapeutic agents. Renowned industrial and academic researchers describe the advantages of nanoparticles as sensing, delivery, image enhancement agents for cancer treatments, and various types of useful nanoparticles such as polymeric nanoparticles and dendrimers.
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Posted in books by kdsaggi on Nov. 08, 2008 // 06:48
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Drug Delivery to the Lung
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This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice. Examines the behavior of inspired spherical particles in the respiratory tract! Featuring over 1300 references, drawings, tables, photographs, and micrographs, Drug Delivery to the Lung · outlines the history of inhaled medications in the treatment of respiratory disease · describes aspects of respiratory structure to inhalation therapy emphasizing developmental changes · compares existing in vitro/in vivo correlations for key aerosol modalities with lung model predictions · discusses particle diameter measurement, particle size statistics, and aerosol test methods · reviews the clinical effects of altering the deposition site of various classes of aerosolized drugs · surveys the development of novel, efficient, and convenient nebulizer systems · details breath-actuated and spacer devices constructed for children · analyzes dry-powder and pressurized metered dose inhalers · considers the transition from CFCs to new environmentally friendly chemical propellants · and more! Giving the clinician an overview of factors essential to understanding drug delivery via nebulization, Drug Delivery to the Lung is a superlative reference for pulmonologists; physiologists; pharmaceutical scientists; immunologists; allergists; analytical, organic, and medicinal chemists and biochemists; chemical, genetic, and process engineers; and medical and graduate school students in these disciplines.
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Posted in books by kdsaggi on Nov. 08, 2008 // 06:49
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Intraocular Drug Delivery
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This reference studies the most recent advances in the development of ocular drug delivery systems. Covering methods to treat or prevent ocular inflammation, retinal vascular disease, retinal degeneration, and proliferative eye disease, this source covers breakthroughs in the management of endophthalmitis, uveitis, diabetic macular edema, and age-related macular degeneration.
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Posted in books by kdsaggi on Nov. 08, 2008 // 06:50
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Dose Optimization In Drug Development
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This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and current research on safety, efficacy, and clinical pharmacology, and PK-PD, this volume critically highlights the multidisciplinary nature of drug development and spans the fields of pharmacokinetics, clinical pharmacology, biostatistics, and experimental medicine.
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Posted in books by kdsaggi on Nov. 08, 2008 // 06:51
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