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Rapid Microbiological Methods in the Pharmaceutical Industry

In recent years there has been increased interest in the possibility of rapid microbiological methods offering enhanced potential error detection capabilities. However, these methods raise a number of questions, such as how to validate new methods, will they be accepted by the pharmacopoeias, and, most importantly, how will the regulators respond? Rapid Microbiological Methods in the Pharmaceutical Industry answers these questions and more. Martin Easter and his panel of experts: § Describe the range of rapid microbiological methods and their applications, including practical tips, and their status regarding validation, established use, and regulatory acceptance § Explore the origins of current methods and the current issues facing the requirements of microbiology and its associated test methods § Delineate the challenges involved in seeking better and more pragmatic methods for the assessment of microbial hazards and risks to ensure product and consumer safety The book assists you in applying an effective system to assess the real microbiological hazards and, hence, quantify realistic risks. Additionally, it provides monitoring methods that will deliver meaningful, useful data for effective decision making in manufacturing, quality assurance, and product safety. The expert and authoritative Read more...
Posted in books by kdsaggi on Sep. 13, 2008 // 06:35 | Comments (0)
Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

Fullerenes and nanotubes are two classes of carbon structures or allotropes, which were discovered about 17 years ago. Since that time, many chemical derivatives have been synthesized using fullerenes and nanotubes as building blocks.

Particularly promising was the theory that the chemical properties of fullerenes, and certain derivatives, made them likely candidates for anticancer drugs, inhibitors of viruses such as HIV, or even as anti-bacterials. Their cyctotoxicity can also be controlled by specific circumstances.

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Posted in books by kdsaggi on Sep. 13, 2008 // 06:38 | Comments (0)
Handbook of Drug Metabolism

Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject from a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the Read more...
Posted in books by kdsaggi on Sep. 13, 2008 // 06:40 | Comments (0)
Screw Compressors: Mathematical Modelling and Performance Calculation

The first part of Screw Compressors gives a review of recent developments in screw compressor design. The second part presents a generalized mathematical definition of screw machine rotors and describes some well known lobe shapes in detail. The third part treats the mathematical modelling of the thermodynamics and fluid mechanics of compression and expansion processes. This includes discussion of the issues addressed in order to be able to predict the optimum rotor size and speed and built-in volume ratio and, in the case of oil flooded machines, the injection position and jet diameter. The fourth and fifth parts discuss the principles used and describe the application of the analytical procedures and rotor profiling techniques, presented in the earlier chapters, to the design of a number of twin screw compressors, currently manufactured including the examples of combining expansion and compression in the same machine.

 

 

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Posted in books by kdsaggi on Sep. 13, 2008 // 10:21 | Comments (2)